Tretinoin Plus™

prescription anti-aging cream

36 grams - 3 month supply

Developed by YoDerm's Medical Director - formulated to help reduce fine lines, discoloration and rough skin.

Single Shipment Price: $90
Subscription Price:
$75 (ships every 3 months)
Choose your frequency

Get Tretinoin Plus only when you want it– on demand or save with recurring shipments every 3 months.

Cancel anytime

Cancelling your subscription is hassle free and at no additional charge. No hidden contracts or commitments.

Free consultations

Your dermatologist is on-demand. They will write prescriptions and answer questions for no additional charge.

"Tretinoin Plus was thoughtfully created with every ingredient in mind. I designed this to be fragrance-free, hypoallergenic and emollient-based so the active ingredients can shine without any unneccessary irritation."
- Dr. Paik, M.D., YoDerm Medical Director
Active Ingredients
More Effective Together
Tretinoin
  • considered the gold standard for treating photoaged skin [1]
  • sheds dead skin cells and promotes collagen growth [2]
  • may improve skin tone and create a "rosy glow" [2]
Plus
Niacinamide
can improve hyperpigmentation
and decrease inflammation [3]
Lactic Acid
promotes gentle exfoliation
allowing ingredients to absorb [4]
Click for a full list of Tretinoin Plus ingredients.

Tretinoin Plus™ is a prescription-strength medication that can only be prescribed by YoDerm dermatologists.

Frequently Asked Questions

Why would my doctor recommend Tretinoin Plus™ instead of Retin-A or generic tretinoin?
Tretinoin Plus™ contains a proprietary blend of tretinoin, niacinamide, and lactic acid, precisely formulated to help with anti-aging. This combination in a rich cream is designed to increase the tolerability and effectiveness of traditional tretinoin used on its own.
How does Tretinoin Plus compare to over-the-counter retinols?
What ingredients are in Tretinoin Plus?
see all Tretinoin Plus FAQs

Possible side effects of Tretinoin Plus

Most common side effects

This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps.Use sunscreen daily and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skin blisters/redness. Wait until your skin has completely recovered from a sunburn before using tretinoin.

Severe side effects

This medication is not recommended for use during pregnancy. Since this drug is absorbed through the skin and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill, knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. YoDerm does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

1. A double-blind randomized study comparing the association of Retinol and LR2412 with tretinoin 0.025% in photoaged skin.

2. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety

3. A Double-Blind, Randomized Clinical Trial of Niacinamide 4% versus Hydroquinone 4% in the Treatment of Melasma

4. Exfoliative Skin-peeling, Benefits from This Procedure and Our Experience
Clinical efficacy and tolerance of topical tretinoin Topical tretinoin improves photoaged skin Topical tretinoin in the treatment of aging skin Comparative Study of Periorbital Wrinkle Treatments Retinoids in the treatment of skin aging Double-blind comparison of 0.1% and 0.025% tretinoin creams